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> home > Products > Primary Antibodies > Antibody Collections > Ribonucleoprotein > M11D1 Antibody (N-term)
M11D1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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- CITATIONS
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- BACKGROUND
Application 
| FC, WB, IHC-P, E |
|---|---|
| Primary Accession | Q9H7H0 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 50734 Da |
| Antigen Region | 88-116 aa |
| Gene ID | 64745 |
|---|---|
| Other Names | Methyltransferase-like protein 17, mitochondrial, 211-, False p73 target gene protein, Methyltransferase 11 domain-containing protein 1, Protein RSM22 homolog, mitochondrial, METTL17, METT11D1 |
| Target/Specificity | This M11D1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-116 amino acids from the N-terminal region of human M11D1. |
| Dilution | FC~~1:10~50 WB~~1:1000 IHC-P~~1:50~100 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | M11D1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | METTL17 {ECO:0000303|PubMed:36482135, ECO:0000312|HGNC:HGNC:19280} |
|---|---|
| Function | Mitochondrial ribosome (mitoribosome) assembly factor (PubMed:36482135, PubMed:38199006). Binds at the interface of the head and body domains of the mitochondrial small ribosomal subunit (mt-SSU), occluding the mRNA channel and preventing compaction of the head domain towards the body (PubMed:36482135). Probable inactive methyltransferase: retains the characteristic folding and ability to bind S-adenosyl-L-methionine, but it probably lost its methyltransferase activity (PubMed:38234605). |
| Cellular Location | Mitochondrion matrix {ECO:0000250|UniProtKB:Q3U2U7} |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
M11D1 may be a component of the mitochondrial small ribosomal subunit.
References
Lim, J., et al. Cell 125(4):801-814(2006)
Saveanu, C., et al. J. Biol. Chem. 276(19):15861-15867(2001)
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$ 385.00
$ 150.00
Cat# AP9974a
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